Body proportions in patients with Turner syndrome on growth hormone treatment

Background: In this cross-sectional study, we aimed to evaluate auxological measurements and detailed body proportions of recombinant human growth hormone (GH)-treated patients with Turner syndrome (TS) compare them a group healthy females. Materials methods: We evaluated 42 TS who received GH treatment 20 controls. Anthropometric were taken target height, mass index (BMI), arm span-height difference, extremity-to-trunk ratio, Manouvrier's skelic calculated. Results: The median (min-max) age the at time evaluation was 13.6 (4.3-20.7) years, control 12.9 (3.8-23.7) years. Height, sitting span significantly lower than those group. Sitting height/height ratio (SHR) in normal ranges both groups BMI higher when compared According index, had shorter legs (p = 0.001). extremity-trunk decreased controls < There no significant difference between karyotype terms these indexes.Conclusion: short stature, increased waist circumference, head ratio. height leg length short; however, SHR standard deviation score (SDS) range. Despite being treated GH, disproportionate stature. disproportion similar short-stature homeobox-containing gene (SHOX) deficiency, which is considered be SHOX haploinsufficiency etiopathogenesis